Three American brothers who have not spoken to each other in a year set off on a train voyage across India with a plan to find themselves and bond with each other -- to become brothers again like they used to be. Their "spiritual quest", however, veers rapidly off-course (due to events involving over-the-counter pain killers, Indian cough syrup, and pepper spray).
Owen Wilson Francis
Adrien Brody Peter
Jason Schwartzman Jack
Amara Karan Rita
Wallace Wolodarsky Brendan
Waris Ahluwalia The Chief Steward
Irrfan Khan The Father
Barbet Schroeder The Mechanic
Camilla Rutherford Alice
Bill Murray The Businessman
Anjelica Huston Patricia
A. P. Singh Taxi Driver
Kumar Pallana Old Man
Dalpat Singh Waiter
Trudy Mathis German Lady #1
Margot Gödrös German Lady #2
Hitesh Sindi Electronics Vendor
Kishen Lal Shoe Vendor
Bhawani Sankar Pepper Spray Vendor
Mukhtiar Bhai Pet Shop Vendor
Suraj Kumar Shoeshine Boy
Kapil Dubey Boy on Bicycle
Mulchand Dedhia Engineer
Dinesh Bishnoi Oldest Boy
Mukesh Bishnoi Middle Boy
Ramesh Bishnoi Youngest Boy
Sriharsh Sharma Boy with Handkerchief
Chanduram Bishnoi Village Elder
Sajjanji Bishnoi Doctor
Pukaram Bishnoi Old Man in Village
Sushila Devi Mother
Ratan Lal Ji Villager
Arun Bishnoi Villager
Jhalaram Bishnoi Villager
Mularam Bishnoi Villager
Anand Pathe Villager
Bhawar Lal Villager
Kaana Ram Villager
Rupa Ram Villager
Shava Ram Villager
Ruka Ram Villager
Bhura Ram Villager
Buramji Ram Villager
Tuka Ram Villager
Bhanwar Singh Villager
Bhanwar Paliwal Villager
Moti Ram Villager
Kishna Ram Villager
Khewal Ram Paliwal Villager
Ravi Acharya Villager
Jai Prakash Sharma Man on Bus
Badhri Dave Hindu Priest
Vincetta Easley Garage Cashier
John Joseph Gallagher Tow Truck Driver
G.B. Singh Pilot
Bhavna Narang Flight Attendant
Sunil Chabra Co-Pilot
Narender Singh Hada Co-Pilot
Thupten Gyatso Oberoi
Gurdeep Singh Chief Steward (Bengal Lancer)
Charu Shankar Stewardess (Bengal Lancer)
Natalie Portman Jack's Ex-Girlfriend