William Blake, an accountant turned fugitive, is on the run. During his travels, he meets a Native American man called Nobody, who guides him on a journey to the spiritual world.
Johnny Depp William Blake
Gary Farmer Nobody
Crispin Glover Train Fireman
Lance Henriksen Cole Wilson
Michael Wincott Conway Twill
Eugene Byrd Johnny 'The Kid' Pickett
John Hurt John Scholfield
Robert Mitchum John Dickinson
Iggy Pop Salvatore 'Sally' Jenko
Gabriel Byrne Charlie Dickinson
Jared Harris Benmont Tench
Mili Avital Thel Russell
Jimmie Ray Weeks Marvin, Older Marshal
Mark Bringelson Lee, Younger Marshal
John North Mr. Olafsen
Alfred Molina Trading Post Missionary
Billy Bob Thornton Big George Drakoulious
Michelle Thrush Nobody's Girlfriend
Steve Buscemi Bartender
Gibby Haynes Man with Gun in Alley
Richard Boes Man with Wrench